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KMID : 0377619630050060665
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Korean Jungang Medical Journal
1963 Volume.5 No. 6 p.665 ~ p.673
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Change of Phosphates contents and transaminase activities of human placenta during the course of gestation.
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Abstract
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One hundred and sixteen human placenta(from the 2nd month to full term) were analyzed to determine the contents of acid soluble phosphorus, lipid-phosphorus, protein phosphorus, nucleic acid (RNA & DNA) phosphorus and the activities of transaminase(GOT & GPT).
The following results ware obtained :
1st Mid. Last (Trimester)
1. Acid soluble-P 29. 5 23. 0 52. 6 mg/100g wet tissue
2. Lipid-P 28.6 27. 6 35.6 mg/100g wet tissue
3. RNA-P 26. 7 23. 0 23.4 mg/100g wet tissue
4. DNA-P 19. 7 23. 0 29. 9 mg/100g wet tissue
5. Protein-P 13. 7 12. 1 13. 9 mg/100g wet tissue
6. GOT 5880 4523 2942 unit/g wet tissue
7. GPT 3757 3187 1957 unit/g wet tissue
The conclusions of this study were summarized as follows :
1. Acid soluble-P of human placenta was 31. 8 mg per 100g of wet tissues in the 2nd month, 61. 9mg in the 10moth(94.7%a increased).
2. Lipid- P of human placenta was 28. 2 mg in the 2nd month, 41. 9mg in the 10th month (48.6 % increased).
3. RNA-P of human placenta was 29. 6 nag in the 2nd month, 22. 9mg in the 10th month (22.6 % decreased) .
4. DNA-P of human placenta was 19.3mg in the 2nd month, 33.4mg in the 10th month (73. 1% increased).
RNA-P/DNA-P ratio was 1.53 in the 2nd month, 0.67 in the 10th month.
5. Protein-P of human placenta was 12-16mg, nothing any noticiable changes, during the gestational course.
6. GOT and GPT activities were observed of decreasing tendency from the 2nd month to the 10th month. GOT was 6660 units per gram of wet tissues in the 2nd month, 2325 units in the 10th
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